Publications

Publications & Posters

The concept of Diagnostics Defining Therapy is a compelling response to the growing challenges of managing infectious disease. Explore our library of featured research, academic discussions, conference abstracts, symposium materials and more.

Media Room

View the SpeeDx library of symposia and presentations from key satellite events and stay up to date with the latest applications of infectious disease diagnostics.

Female speaker at conference

Key Publications

You can find an extensive list of independent and collaborative publications related to SpeeDx products and technology. Below is a collection of key research and clinically relevant data that is shaping the management of infectious disease around the world.

PlexPCR® SARS-CoV-2

PlexPCR® VHS

  • Performance characteristics of the SpeeDx PlexPCR VHS assay for the molecular detection of herpes simplex virus, varicella zoster virus, and Treponema pallidum in lesion swabs
    Goldstein EJ et al Diagn Microbiol Infect Dis. 2020; 99(2):115221
    Link

 

ResistancePlus® MG

  • Resistance-Guided Antimicrobial Therapy Using Doxycycline–Moxifloxacin and Doxycycline–2.5 g Azithromycin for the Treatment of Mycoplasma genitalium Infection: Efficacy and Tolerability.
    Durukan et al. Clin Infect Dis. 2020; 71(6):1461–1468.
    Link
  • Outcomes of Resistance-guided Sequential Treatment of Mycoplasma genitalium Infections: A Prospective Evaluation.
    Read TRH et al. Clin Infect Dis. 2019; 68(4):554-560.
    Link
  • Mycoplasma genitalium: high prevalence of resistance to macrolides and frequent anorectal infection in men who have sex with men in western Sydney.
    Couldwell DL et al. Sex Trans Dis, 2018; 94:406-410
    Link
  • Prevalence of Mycoplasma genitalium and Azithromycin-Resistant Infections Among Remnant Clinical Specimens, Los Angeles.
    Allan-Blitz LT et al. BMJ: Sex Trans Infect, 2018; 45(9):632-635
    Link

 

ResistancePlus® GC

  • Reflex detection of ciprofloxacin resistance in Neisseria gonorrhoeae using the SpeeDx ResistancePlus GC Assay.
    Lee, D.Y.J et al. Journal of Clinical Microbiology 2021 Mar 3;JCM.0089-21.
    Link
  • Evaluation of the molecular detection of ciprofloxacin resistance in Neisseria gonorrhoeae by the ResistancePlus GC assay (SpeeDx)
    Cotton, S et al. Diagnostic Microbiology and Infectious Diseases 2020 Nov 12;99(4):115262
    Link
  • Improved determination of Neisseria gonorrhoeae gyrase A genotype results in clinical specimens.
    Allan-Blitz LT et al J Antimicrob Chemother. 2019; 74(10):2913-2915
    Link
  • Evaluation of the ResistancePlus GC (beta) assay: a commercial diagnostic test for the direct detection of ciprofloxacin susceptibility or resistance in Neisseria gonorrhoeae.
    Ebeyan S et al J Antimicrob Chemother. 2019; 74(7):1820-1824
    Link

 

 

Technology

  • MNAzyme qPCR with superior multiplexing capacity.
    Mokany E et al. Clin. Chem., 2013; 59(2); 419-426
    Link
  • MNAzymes are a versatile new class of nucleic acid enzymes which can function as biosensors and molecular switches.
    Mokany E et al. J. Am. Chem. Soc., 2010; 132(3); 1051-1059
    Link
  • Superior Multiplexing Capacity of PlexPrimers Enables Sensitive and Specific Detection of SNPs and Cluster Mutations in qPCR.
    Tan LY et al. PLOS One January 23rd, 2017
    Link

Posters

SpeeDx products have been featured in posters and presentations at conferences around the globe. See a selection of key publications below, please contact your local technical representative for more information.

ResistancePlus® MG

  • Lack of demonstrated Clinical Value in Pre-Treatment Determination of the Presence of parC Mutations in Mycoplasma genitalium –  Bone S et al IUSTI (Bucharest) 2020
    View the Poster (PDF)
  • A clinical evaluation of ResistancePlus® MG FleXible for simultaneous detection of Mycoplasma genitalium and macrolide resistance –  Ferndandez-Huerta M et al IUSTI (Bucharest) 2020
    View the Poster (PDF)
  • A primary investigation of Mycoplasma genitalium coinfection with Chlamydia trachomatis in southern Denmark – Chen M et al ECCMID (Madrid) 2018
    View the Poster (PDF)
  • Mycoplasma genitalium in asymptomatic people with sexual risk behaviours; screen or not to screen, that’s the question – Fernández-Huerta M et al ECCMID (Madrid) 2018
    View the Poster (PDF)
  • Mycoplasma genitalium in Scotland 2018 – Templeton K BASHH (Edinburgh) 2018
    View the Poster (PDF)

 

ResistancePlus® GC

  • Evaluation of the ResistancePlus® GC test which enables targeted use of ciprofloxacin for Neisseria gonorrhoeae treatment – Mokany E et al ECCMID (Madrid) 2019
    View the Poster (PDF)
  • Guiding Neisseria gonorrhoeae management by molecular detection of ciprofloxacin resistance by ResistancePlus GC assay (SpeeDx) – Cotton S et al ECCMID (Madrid) 2018
    View the Poster (PDF)
  • The evaluation of ResistancePlus GC (beta) assay for the detection of gonorrhoea ciprofloxacin resistance and susceptibility – Tan L et al STI&HIV World Congress (Vancouver) 2019
    View the Poster (PDF)

 

PlexPCR® VHS

  • Performance characteristics of the PlexPCR® VHS assay for the detection of Treponema pallidum and other pathogens in genital and extragenital lesions – Qquellon-Palacios J et al STI & HIV 2021 World Congress 14th-17th July 2021
    View the Poster (PDF)
  • Genital lesion producing pathogens diagnosed using PlexPCR – Tan L et al MMM (Sydney) 2018
    View the Poster (PDF)
  • SpeeDx PlexPCR® VHS Evaluation – Vipond B et al IUSTI (Helsinki) 2017
    View the Poster (PDF)
  • Multiplex assay for the detection of syphilis and other pathogens associated with genital lesions using PlexPCR® – Windsor M et al IUSTI World (Rio) 2017
    View the Poster (PDF)

 

PlexPCR® RespiVirus

  • Clinical Prospective Study comparing In-house Respiratory Viral Assays With a Highly Multiplexed Commercial Assay developed by SpeeDx – Nair S et al ECMID (Vienna) 2017
    View the Poster (PDF)

 

SpeeDx Blue Sky & Pipeline

  • A rapid test for susceptibility to bacteriostatic and bactericidal antibiotics – Lima N et al ASA (Melbourne) 2020
    View the Poster (PDF)
  • Determination of antibiotic susceptibility and efficacy by VITA – Lima N et al STI&HIV World Congress (Vancouver) 2019
    View the Poster (PDF)
  • PlexZymes: versatile biosensors for target detection – Hasick et al Biosensors conference (Gothenburg) 2016
    View the Poster (PDF)
Learn more about SpeeDx Publications & Media