Streamlined STI Research

With SpeeDx CT/GC/TV/MGPlex, maximize STI organism detection and couple with AMR assays. Streamline your workflow whilst keeping up with sample throughput with this cost-effective solution.

Streamline STI Research 

Maximize organism detection and couple with AMR mutation results

Chlamydia trachomatis (CT), Neisseria gonorrhoeae (GC), Trichomonas vaginalis (TV), and Mycoplasma genitalium (MG) are important sexual health organisms that cause infections and complications for millions of people around the globe every year1. A growing concern is the increased resistance to antibiotics that these organisms can acquire, resulting in reduced treatment options and further spread of infection2. Research focussing on anti-microbial markers aids understanding and helps monitor the prevalence of Antimicrobial Resistant (AMR) organisms.

 

CT/GC/TV/MGPlex

The CT/GC/TV/MGPlex assay enables detection of these four key STI organisms, and the ability to use the same sample extraction to determine antibiotic resistance utilizing SpeeDx’s flagship Antimicrobial Resistance (AMR) products:

PlexPrime® GC+gyrA

STIPlex MG+23S

Scientist placing PCR plate into thermocycler

Streamline sample throughput

Maximize processing with a single-well multiplex in a 96-well plate
  • Don’t use multiple assays and multiple workflows for your research, take advantage of the CT/GC/TV/MGPlex single well, multiplex qPCR assay, to detect four key STI-causing organisms. This assay is powered by proprietary PlexPCR technology, which improves multiplex performance compared with other probe-based tests3.
  • Increase your productivity by running up to 96 reactions in a single plate.
  • Thoughtful 192 reaction pack size will suit your laboratory’s throughput needs. Simplifying stock ordering, reducing reagent wastage and minimizing required storage space.

Streamline your workflow

Reduce Hands-on Time and human error with PlexPrep® automation
  • Get up and running today! Designed for open platforms, you can easily integrate the CT/GC/TV/MGPlex assay into your existing research workflow, reducing time to implementation.
  • Streamline your research workflow and increase productivity for rapid identification. Option to include PlexPrep®automation to reduce manual processes, like sample handling, extraction set-up and qPCR set-up. Like others, realize increased sample throughput when utilizing a PlexPrep® / open platform workflow, in conjunction with a 19% decrease in hands-on-time per reportable result when processing large sample numbers4.
  •  Scalable workflow to suit your throughput. Easily add more instruments to grow with your needs.

Streamline costs

Utilize open platforms and maximize your STI multiplexing capabilities
  • SpeeDx multiplexing technology utilizes universal probes, a key feature in reducing the cost of producing assays. We pass this benefit on to you to keep assays affordable.
  • The CT/GC/TV/MGPlex assay is adaptable to most laboratory workflows. Compatible with magnetic bead-based extraction, manual or PlexPrep® assisted liquid handling, followed by amplification on ABI 7500 and QuantStudio 5 and 7 systems, makes this assay quick and easy to implement within most research laboratories.
  • Utilize existing instrumentation that may be underutilized in the laboratory. Reduce implementation costs by avoiding acquisition of new equipment and associated service contracts.

CT/GC/TV/MGPlex is Research Use Only (RUO), not for use in diagnostic procedures.

References

1. Chesson HW, Mayaud P, Aral SO. Sexually Transmitted Infections: Impact and Cost-Effectiveness of Prevention. In: Holmes KK, Bertozzi S, Bloom BR, et al., editors. Major Infectious Diseases. 3rd edition. Washington (DC): 2017 Nov 3. Chapter 10.2.

2. Growing antibiotic resistance forces updates to recommended treatment for sexually transmitted infections. Geneva, Switzerland; World Health Organization: August 30, 2016

3. Tan LY et al, PLOS ONE. 2017; 12(1): e0170087.

4. Todd M. Pryce, Erin J. Haygarth, Jessica Bordessa and Peter A. Boan. “Evaluation of a PlexZyme-Based PCR Assay and Assessment of COVID-19 Surge Testing Throughput Compared to Cobas SARS-CoV-2.” Pathogens 2021, 10, 1088. https://doi.org/10.3390/pathogens10091088

Want to Streamline STI Solutions in your laboratory?