Discover the difference with PlexPrime® SARS-CoV-2 Genotyping*

Research reagents to support investigation of COVID-19 variants of concern

PlexPrime® products – powered by PlexZyme® & PlexPrime® technology – offer superior multiplex mutation detection. Our patented priming approach generates unique amplicons for target specific amplification and detection, improving specificity even across clustered mutations. Multiplexing key mutations for single-well detection further streamlines your testing process.


Choose PlexPrime® technology and place your lab at the forefront of SARS-CoV-2 mutation detection.

Product Availability
PlexPrime® SARS-CoV-2 Alpha/Beta/Gamma+* Available now
PlexPrime® SARS-CoV-2 P681R Delta* Available now
PlexPrime® SARS-CoV-2 L452Q Lambda* Available now

*PlexPrime® products are research use only, not for use in diagnostic procedures
The PlexPrime® SARS-CoV-2 Alpha/Beta/Gamma+ components also identify Omicron variants, including BA.2

Clear the path towards enhanced laboratory efficiency and support public health measures in response to the COVID-19 pandemic.

PlexPrime® SARS-CoV-2 Genotyping reagents are designed to detect mutations associated with variants of concern (VOC). VOCs are linked to increased transmissibility or severity of disease. PlexPrime® mutation detection products  generate actionable, reportable data in only a few hours, enabling proactive management of public health crises. 

Increase laboratory productivity

Improve throughput and minimise hands-on time by reducing the number of reflex reactions required in your variant investigations. 

PlexPrime® SARS-CoV-2 Genotyping allows for detection of multiple mutations linked to VOC in a single well using only a small amount of sample extract. 


  • Streamline testing – Realise efficiency through multiplex solutions, process more samples per plate, and easily respond to test number fluctuations or periodic surges in COVID-19 cases
  • Preserve valuable extract – Minimize the number of reactions required to detect key mutations, plus each multiplexed well requires only 20µl of sample extract.
  • Have confidence in your results with superior technology – Our PlexPrime® technology enables simultaneous multiplex mutation detection in a single well without compromising on specificity or sensitivity.

Focus your sequencing efforts

Reduce the cost, time, and complexity of sequence-based variant analysis. Sequencing is key to support ongoing variant monitoring, but is an unsustainable long-term solution for large amounts of SARS-CoV-2- positive samples. 

Use PlexPrime® SARS-CoV-2 Genotyping products to identify key mutations and clear a path for sequencing the correct positive samples. 


  • Resource management – Identify the positives of interest and reduce the burden on your highly skilled staff
  • Value – Focus data collection efforts using your existing qPCR platform – smarter sequencing reduces overall laboratory costs.

sars-cov-2 genotyping graph

We routinely monitor and assess emerging variants of concern and high consequence, to continually develop appropriate detection tools for key mutations. The versatility of our PlexPrime® technology supports rapid evolution of our SARS-CoV-2 Genotyping solutions as additional variants of concern are designated. 

PlexZyme binding to target and cleaving a probe

Security of Supply

Supply chains have been increasingly strained throughout the COVID-19 pandemic. SpeeDx PlexPCR® technology de-couples the detection probe from the target sequence – resulting in universal probes suited for multiple assays and applications.

  • Streamlined manufacturing – We manufacture in bulk to support high volume ordering and demand fluctuations.
  • Unique technology – Our universal-probe approach ensures no interruptions to your daily testing and secures supply of essential reagents for your laboratory.

*PlexPrime® products are research use only, not for use in diagnostic procedures

Contact SpeeDx to streamline your variant workflow