AACC 2016

Simultaneous detection of Mycoplasma genitalium and mutations associated with macrolide resistance has the potential to improve patient management Todd et al
Todd et al poster AACC    download poster  download abstract
Background: In the 2015 CDC STD treatment guidelines, Mycoplasma genitalium (Mg) was highlighted as an emerging issue based on increasing evidence linking it with nongonococcal urethritis (NGU) in men and cervitis in women. However, to-date diagnosis has been difficult as it is a slow growing organism and can take up to 6 months to culture. It has only been with the advent of NAAT testing that routine detection has been made possible… read more


Multiplex assay for the simultaneous detection of Mycoplasma genitalium and macrolide resistance using PlexPCR Tabrizi et al
Tabrizi et al poster ECCMID  download poster  download abstract
Objectives: Treatment of M. genitalium (Mg) infection with single dose 1 g macrolide antibiotic, azithromycin, is routinely utilized in clinical practice. However, widespread use of azithromycin has been associated with emergence of macrolide resistance and ineffective cure rates. Mutations at two positions, 2058 and 2059 (E. coli numbering), in the 23S rRNA gene of Mg have been associated with macrolide resistance. Simultaneous detection of these mutations with identification of Mg offers greater clinical utility and could be used to direct more effective and appropriate treatment… read more