Publications

Key Publications

ResistancePlus®

Highlighting the clinical need for diagnosing Mycoplasma genitalium infection.
Ison C.A., Fifer H., Gwynn S., Horner P., Muir P., Nicholls J., Radcliffe K., Ross J., Taylor-Robinson D., White J. (2018). Int J STD AIDS. Article first published online: February 10
Link | Summary

Syndromic management of STIs and the threat of untreatable Mycoplasma genitalium.
Bradshaw CS., Horner P.J., Jensen J.S., White P.J. Lancet Infect Dis. 2018 Mar;18(3):251-252.
Link | Summary

A silent epidemic: the prevalence, incidence and persistence of Mycoplasma genitalium among young, asymptomatic high-risk women in the United States.
Seña A.C., Lee J.Y., Schwebke J., Philip S.S., Wiesenfeld H.C., Rompalo A.M., Cook R.L., Hobbs M.M. Clin Infect Dis. 2018 Jan 12.
Link | Summary

Mycoplasma genitalium on the Loose: Time to Sound the Alarm.
Manhart L.E. Sex Transm Dis. 2017 Aug;44(8):463-465.
Link | Summary

Antimicrobial-resistant sexually transmitted infections: gonorrhoea and Mycoplasma genitalium.
Jensen J.S. & Unemo M. 2017. Nature Review Urology January 10th.
Link | Summary

European guideline on Mycoplasma genitalium infections.
Jensen J.S., Cusini M., Gomberg M. 2016. IUSTI June 2nd.
Link

High Macrolide Resistance in Mycoplasma genitalium Strains Causing Infection in Auckland, New Zealand.
Basu, I., Roberts, S. A., Bower, J. E., Henderson, G., & Reid, M. (2017). Journal of Clinical Microbiology, 55(7), 2280-2282.
Link

Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment.
Charlotte A Gaydos. (2017); The Journal of Infectious Diseases, Volume 216, Issue suppl_2, Pages S406–S411,
Link

Evaluation of a commercial multiplex quantitative PCR (qPCR) assay for simultaneous detection of Mycoplasma genitalium and macrolide resistance-associated mutations in clinical specimens.
Le Roy, C., Hénin, N., Bébéar, C., & Pereyre, S. (2017). Journal of clinical microbiology, 55(3), 978.
Link

Prevalence of mycoplasma genitalium and macrolide resistance in asymptomatic men who have sex with men (MSM) attending a sexual health centre.
Read, T. R., Fairley, C. K., Murray, G., Danielewski, J., Su, J., Doyle, M., … & Mokany, E. (2017). O12. 4
Link

Prospective evaluation of ResistancePlus MG, a new multiplex quantitative PCR assay for detection of Mycoplasma genitalium and macrolide resistance.
Tabrizi, S. N., Su, J., Bradshaw, C. S., Fairley, C. K., Walker, S., Tan, L. Y., … & Garland, S. M. (2017). Journal of clinical microbiology, 55(6), 1915-1919.
Link | Summary

Multiplex assay for simultaneous detection of Mycoplasma genitalium and macrolide resistance using PlexZyme and PlexPrime technology.
Tabrizi S., Tan Y.L., Walker S., Twin J., Poljak M., Bradshaw C.S., Fairley C.K., Bissessor M., Mokany E., Todd A.V., Garland S.M., 2016. PLOS ONE June 6th.
Link | Summary


PlexZyme®

Mokany E., Tan Y.L., Bone S.M., Fuery C., Todd A.V., 2013. MNAzyme qPCR with superior multiplexing capacity. Clin. Chem. 59(2); 419-426
Link | Supplementary Information

Mokany E., Bone S.M., Young P.E., Doan T.M., Todd A.V., 2010. MNAzymes are a versatile new class of nucleic acid enzymes which can function as biosensors and molecular switches. J. Am. Chem. Soc. 132(3); 1051-1059
Link |Supplementary Information

Tan L. Y., Walker S. M., Lonergan T., Lima N. E., Todd A. V. Mokany E. 2017. Superior Multiplexing Capacity of PlexPrimers Enables Sensitive and Specific Detection of SNPs and Cluster Mutations in qPCR. PLOS One January 23rd.
Link


Signal Amplification

Linardy E.M., Erskine S.M., Lima N.E., Lonergan T., Mokany E., Todd A.V., 2016. EzyAmp signal amplification cascade enables isothermal detection of nucleic acid and protein targets. Biosens. Bioelectron. 75; 59-66
Link

Bone S.M., Lima N.E., Todd A.V., 2015. DNAzyme switches for molecular computation and signal amplification. Biosens. Bioelectron. 70; 330-337
Link

Bone S.M., Todd A.V., 2014. MNAzymes provide a universal mechanism for triggering DNAzyme synthesis cascades. Chem. Comm. 50(87); 13243-13246
Link

Bone S.M., Hasick N.J., Lima N.E., Erskine S.M., Mokany E., Todd A.V., 2014. DNA-only Cascade: a universal tool for signal amplification, enhancing the detection of target analytes. Anal. Chem. 86(18); 9106-9113
Link


Related Publications

Zagorovsky K. and Chan W.C.W. 2013. A plasmonic DNAzyme strategy for point-of-care genetic detection of infectious pathogens. Angew. Chem. 52(11); 3168-3171
Link

Kahan-Hanum M., Douek Y., Adar R., Shapiro E. 2013. A library of programmable DNAzymes that operate in a cellular environment. Sci Rep. 3; 1535 Gerasimova Y.V. and Kolpashchikov D.M. 2010. Nucleic acid detection using MNAzymes. Chem. Biol. 17(2); 104-106
Link

Nauwelaers D., Vjigen L., Atkinson C., Todd A., Geretti A.M., Van Ranst M., Stuyver L. 2009. Development of a real-time multiplex RSV detection assay for difficult respiratory samples, using ultrasone waves and MNAzyme technology
Link